Reassessing the conventional fertilisation check: leveraging PGT-A to increase the number of transferrable embryos
DOI:10.1016/j.rbmo.2024.104595 by Reproductive BioMedicine Online in 2025
[2624]
Key Points
see Q&A
58
“No result” after PGT-A is a rare observation
60
Having more blastocysts to biopsy per patient was found to be a significant predictor of “no result” embryos
140
Over 40% of the tested non-2PN embryos were euploid.
141
Embryos resulting from 1PN zygotes were more likely to be haploid
142
Embryos resulting from 3PN and 4PN zygotes were more likely to be polyploid
143
Maternal origin of polyploidy was more common in ICSI cases
ClassRoom
Preimplantation genetic testing for aneuploidy in patients of different age: a systematic review and meta-analysis
DOI:10.5468/ogs.24028 by Obstetrics & Gynecology in 2024
[1277]
A multicenter, prospective, blinded, nonselection study evaluating the predictive value of an aneuploid diagnosis using a targeted next-generation sequencing–based preimplantation genetic testing for aneuploidy assay and impact of biopsy
DOI:10.1016/j.fertnstert.2020.07.052 by Fertility and Sterility in 2021
[1272]
The Technological Advances in Embryo Selection and Genetic Testing: A Look Back at the Evolution of Aneuploidy Screening and the Prospects of Non-Invasive PGT
DOI:10.3390/reprodmed2010004 by Reproductive Medicine in 2023
[171]
TextBook
Impacts of double biopsy and double vitrification on the clinical outcomes following euploid blastocyst transfer: a systematic review and meta-analysis
DOI:10.1093/humrep/deae235 by Human Reproduction in 2024
[1299]
Healthy Live Births after the Transfer of Mosaic Embryos: Self-Correction or PGT-A Overestimation?
DOI:10.3390/genes15010018 by Genes (Basel). in 2024
[968]
Advancements and Applications of Preimplantation Genetic Testing in In Vitro Fertilization: A Comprehensive Review
DOI:10.7759/cureus.57357 by Cureus. in 2024
[852]
Association between Embryo Development and Chromosomal Results from PGT-A in Women of Advanced Age: A Prospective Cohort Study.
DOI:10.3390/jcm13020626 by Journal of Clinical Medicine in 2024
[732]
Higher live birth rates are associated with normal BMI in PGT-A FET cycles: a SART CORS study
DOI:10.1016/j.fertnstert.2023.11.005 by Fertility and Sterility in 2023
[700]
High-resolution PGT-A results in incidental identification of patients with small pathogenic copy number variants
DOI:10.1007/s10815-023-02969-8 by Journal of Assisted Reproduction and Genetics in 2023
[634]
Embryo drop-out rates in preimplantation genetic testing for aneuploidy (PGT-A): a retrospective data analysis from the DoLoRes study
DOI:10.1007/s10815-023-02976-9 by Journal of Assisted Reproduction and Genetics in 2023
[541]
Infertility clinics and acupuncture: a qualitative web-based study
DOI:10.1007/s10815-023-02898-6 by Journal of Assisted Reproduction and Genetics in 2023
[1]
Recent Publications
The evolution of preimplantation genetic testing: where is the limit?
DOI:10.1016/j.rbmo.2025.104845 by Reproductive BioMedicine Online in 2025
[2697]
A Review of Cost-Effectiveness of Preimplantation Genetic Testing for Aneuploidy
DOI:10.1097/OGX.0000000000001373 by Obstetrical & Gynecological Survey in 2025
[2659]
Embryos With "No Result" After PGT-A: A Retrospective Analysis of Causative Factors
DOI:10.1155/ogi/4043963 by Obstetrics and Gynecology International in 2025
[2658]
Routine detection of consanguinity through preimplantation genetic testing in human embryos
DOI:0.1016/j.rbmo.2024.104453 by Journal of Assisted Reproduction and Genetics in 2025
[2638]
Reassessing the conventional fertilisation check: leveraging PGT-A to increase the number of transferrable embryos
DOI:10.1016/j.rbmo.2024.104595 by Reproductive BioMedicine Online in 2025
[2624]
The diagnostic accuracy of preimplantation genetic testing (PGT) in assessing the genetic status of embryos: a systematic review and meta-analysis
DOI:10.1186/s12958-025-01376-1 by Journal of Assisted Reproduction and Genetics in 2025
[2618]
Prenatal diagnosis following preimplantation genetic testing (PGT): recommendations of the Italian Society of Human Genetics (SIGU)
DOI:10.1007/s10815-024-03358-5 by Journal of Assisted Reproduction and Genetics in 2025
[2549]
PGT-A: what's it for, what's wrong?
DOI:10.1007/s10815-025-03400-0 by Journal of Assisted Reproduction and Genetics in 2025
[2535]
Impact of aneuploidy on reproductive success in young infertile women: prospective analysis
DOI:10.1016/j.rbmo.2024.103858 by Reproductive BioMedicine Online in 2024
[2450]
Greater PGT-A utilization in IVF clinics does not improve live birth rates but relates to IVF center ownership: a preliminary report
DOI:10.1007/s10815-024-03340-1 by Journal of Assisted Reproduction and Genetics in 2024
[2408]
Aneuploidy rates and clinical pregnancy outcomes after preimplantation genetic testing for aneuploidy using the progestin-primed ovarian stimulation protocol or the gonadotropin-releasing hormone antagonist protocol
DOI:10.1016/j.jogoh.2024.102883 by Journal of Gynecology Obstetrics and Human Reproduction in 2024
[2336]
Polar body-based PGT-A: not dead yet? A step forward back to the roots of PGT-A
DOI:10.1016/j.rbmo.2024.104430 by Reproductive BioMedicine Online in 2024
[2230]
Reproductive outcomes after preimplantation genetic testing in couples with sex chromosome abnormalities: a retrospective cohort study of 83 couples
DOI:10.1007/s10815-024-03303-6 by Journal of Assisted Reproduction and Genetics in 2024
[2219]
A method for determining potential parental contamination: linkage disequilibrium-based log-likelihood ratio analysis for IVF-PGT
DOI:10.1186/s12958-024-01300-z by Reproductive Biology and Endocrinology in 2024
[2181]
Impact of blastocyst grading and blastocyst biopsy dates on the clinical outcomes of patients undergoing preimplantation genetic testing
DOI:10.3389/fendo.2024.1427922 by Frontiers in Endocrinology (Lausanne) in 2024
[2106]
Impacts of double biopsy and double vitrification on the clinical outcomes following euploid blastocyst transfer: a systematic review and meta-analysis
DOI:10.1093/humrep/deae235 by Human Reproduction in 2024
[2105]
Success Rates with Preimplantation Genetic Testing for Aneuploidy (PGT-A) in Good Prognosis Patients is Dependent on Age
DOI:10.1016/j.fertnstert.2024.09.043 by Fertility and Sterility in 2024
[2062]
Clinical-grade whole genome sequencing-based haplarithmisis enables all forms of preimplantation genetic testing
DOI:10.1038/s41467-024-51508-1 by Nature Communications in 2024
[1854]
Lessons learned from 64,071 embryos subjected to PGT for aneuploidies: results, recurrence pattern and indications analysis
DOI:10.1016/j.rbmo.2024.103979 by Reproductive BioMedicine Online in 2024
[1806]
PGT-A is Associated with Reduced Live Birth Rates in Fresh but not Frozen Donor Oocyte IVF cycles: An Analysis of 18,562 Donor Cycles Reported to SART CORS
DOI:10.1016/j.fertnstert.2024.08.315 by Fertility and Sterility in 2024
[1667]
The current clinical applications of preimplantation genetic testing (PGT): acknowledging the limitations of biology and technology
DOI:10.1080/14737159.2024.2390187 by Expert Review of Molecular Diagnostics in 2024
[1625]
Webinars
Essential knowledge: Management of PGT-A cycle [ESHRE]
ESHRE
PGT Misdiagnosis Rates [Cooper Surgical]
Cooper Surgical
The Past and Present of PGT-A [Cooper Surgical]
Cooper Surgical
Embryo Quality Control with PGT-A Plus [Igenomix]
VITROLIFE
Precision Parenting: Powering Pre-Implantation Diagnosis with Whole Genome Sequencing [Progenesis]
Progensis
IVF Alerts
Reproductive Treatment in Restrictive Times: Utilization of Pre-Implantation Genetic Testing After Dobbs
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Patient dies after receiving gene therapy for Duchenne muscular dystroph
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Published in: 36
[ID: 50]
We must not ignore eugenics in our genetics curriculum, says professor
