microRNA analysis from spent embryo culture media (SECM) showed a slightly increased metabolic activity in the group with unsuccessful embryo implantation group.
150
The culture medium provides the extracellular environment for early embryo development during IVF cultivation
151
The set of molecules secreted by the embryo into its extracellular environment is known as the embryo secretome
152
It is well established that during development in the culture medium, the embryo consumes certain amino acids for growth while releasing other amino acids
153
The expression level of miR-16-5p was significantly upregulated in the SECM group with an unsuccessfully implanted embryo from day 5 after fertilization.
TextBook
Advancements and Challenges in Preimplantation Genetic Testing for Aneuploidies: In the Pathway to Non-Invasive Techniques
DOI:10.3390/genes15121613 by Genes (Basel). in 2025
[1367]
Current research status and clinical applications of noninvasive preimplantation genetic testing: A review
DOI:10.1097/MD.0000000000039964 by Medicine (Baltimore) . in 2024
[1319]
Non-invasive preimplantation genetic testing for aneuploidy: is the promise real?
DOI:10.1093/humrep/deae151 by Human Reproduction in 2024
[1029]
Recent Publications
New approaches in the analysis of spent embryo culture media in the IVF process
DOI:10.1007/s00404-025-08017-3 by Archives of Gynecology and Obstetrics in 2025
[2693]
Could metabolic imaging and artificial intelligence provide a novel path to non-invasive aneuploidy assessments? A certain clinical need
DOI:10.1071/RD24122 by Reproduction, Fertility and Development in 2025
[2550]
Comparison of Non-Invasive and Minimally Invasive Preimplantation Genetic Testing for Aneuploidy Using Samples Derived from the Same Embryo Culture
DOI:10.3390/jcm14010033 by Journal of Clinical Medicine in 2025
[2502]
Advancements and Challenges in Preimplantation Genetic Testing for Aneuploidies: In the Pathway to Non-Invasive Techniques
DOI:10.3390/genes15121613 by Genes (Basel). in 2025
[2487]
Non-invasive prediction of human embryonic ploidy using artificial intelligence: a systematic review and meta-analysis
DOI:10.1016/j.eclinm.2024.102897 by eClinicalMedicine in 2024
[2301]
Non-invasively predicting euploidy in human blastocysts via quantitative 3D morphology measurement: a retrospective cohort study
DOI:10.1186/s12958-024-01302-x by Reproductive Biology and Endocrinology in 2024
[2212]
Current research status and clinical applications of noninvasive preimplantation genetic testing: A review
DOI:10.1097/MD.0000000000039964 by Medicine (Baltimore) . in 2024
[2209]
Non Invasive Preimplantation Testing for Aneuploidies in Assisted Reproduction: A SWOT Analysis
DOI:10.1007/s43032-024-01698-2 by Reproductive Science in 2024
[2180]
Development of a PCR-based method to identify fetal sex during IVF cycles
DOI:10.1017/S096719942400011X by Zygote. in 2024
[1975]
Efficacy of non-invasive chromosome screening, preimplantation genetic testing for aneuploidy, and morphological grading in selecting embryos of patients with advanced maternal age: a three-armed prospective cohort study
DOI:10.1186/s12884-024-06736-0 by BMC Pregnancy and Childbirth in 2024
[1714]
Analyzing Cell-free Genomic DNA in Spent Culture Media: Noninvasive Insight into the Blastocysts
DOI:10.1055/s-0044-1788260 by Global Medical Genetics in 2024
[1493]
Non-invasive preimplantation genetic testing for aneuploidy: is the promise real?
DOI:10.1093/humrep/deae151 by Human Reproduction in 2024
[1321]
Webinars
EMBRACE: what to expect from embryo viability and clinical outcomes in a niPGT-A program. [Igenomix]
