Reproductive output of old males is limited by seminal fluid, not sperm number
DOI:10.1093/evlett/qrae071 by Evolution Letters in 2025
[2639]
Key Points
see Q&A
114
Male reproductive senescence is typically characterized by a decline in the number of sperm produced and transferred by old males
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Seminal fluid, rather than sperm number, limits reproductive success in old or multiply mating males, highlighting its underappreciated role in reproductive aging.
TextBook
Intravaginal exposure to seminal plasma after ovum pick up does not increase live birth rates after IVF or ICSI: a double-blind, placebo-controlled randomized tria
DOI:10.1016/j.fertnstert.2024.02.002 by Fertility and Sterility in 2024
[735]
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Reproductive output of old males is limited by seminal fluid, not sperm number
DOI:10.1093/evlett/qrae071 by Evolution Letters in 2025
[2639]
Seminal plasma induces receptivity-associated genes and pathways in endometrial epithelial organoids
DOI:10.1016/j.rbmo.2025.104982 by Reproductive BioMedicine Online in 2025
[2636]
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[2200]
The efficacy and functional consequences of interactions between human spermatozoa and seminal fluid extracellular vesicles
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[1861]
IVF Alerts
Reversing age-related fertility decline in male fruit flies: The crucial role of seminal fluid
