When comparing a freeze-all strategy with a fresh transfer strategy in a randomized controlled trial setting, no significant difference was found in the cumulative live birth rates between the two strategies
182
In addition, time to pregnancy was shorter in the fresh transfer group compared with the freeze-all strategy group when looking cumulatively at the complete cycle.
183
Also speaking against a ‘freeze-all’ for all policy is the higher risk of pregnancy and obstetric complications, with FET singletons are more likely to be large for gestational age and have a higher mean birthweight.
TextBook
Fresh versus Frozen Embryo Transfer in In Vitro Fertilization/Intracytoplasmic Sperm Injection Cycles: A Systematic Review and Meta-Analysis of Neonatal Outcomes
DOI:10.3390/medicina60081373 by Medicina (Kaunas). in 2024
[1195]
Should we still perform fresh embryo transfers in ART?
DOI:10.1093/humrep/dez233 by Human Reproduction in 2019
[204]
Recent Publications
Cumulative live birth rates in a freeze-all or fresh transfer strategy after one complete ART cycle in ovulatory women: secondary outcome of a randomised controlled trial
DOI:10.1016/j.rbmo.2024.104449 by Reproductive BioMedicine Online in 2024
[1983]
Fresh versus Frozen Embryo Transfer in In Vitro Fertilization/Intracytoplasmic Sperm Injection Cycles: A Systematic Review and Meta-Analysis of Neonatal Outcomes
DOI:10.3390/medicina60081373 by Medicina (Kaunas). in 2024
[1832]
Embryo transfer impact: a comprehensive national cohort analysis comparing maternal and neonatal outcomes across varied embryo stages in fresh and frozen transfers
DOI:10.3389/fendo.2024.1400255 by Frontiers in Endocrinology (Lausanne) in 2024
